【关键词】糖尿病视网膜病变; 视网膜激光光凝术; 沃丽汀; 视力; 视网膜局部微循环
【中图分类号】Ｒ779． 63; Ｒ587． 2 【文献标志码】AClinical effect of retinal laser photocoagulation combined with Volitin on diabetic retinopathy XIANG Yi-min，DAI Hong-quan ( Department of Ophthalmology，Fuling Central Hospital，Chongqing 408000，China) 【Abstract】Objective: To observe the effects of retinal laser photocoagulation combined with Voritin on the vision，local retinal microcirculation and serum factors of diabetic retinopathy． Methods: 160 patients with diabetic retinopathy were divided into control group and observation group according to different treatment methods，80 cases in each group． The control group was treated with retinal laser photocoagulation，and the experimental group was treated with Voritin on the basis of the control group． The index of macular reti- nal thickness ( CMT) ，best corrected visual acuity ( BCVA) ，retinal microcirculation indexes ［peak systolic velocity( PSV) ，end-dias- tolic velocity( EDV) ，resistance index( ＲI) ］，serum interleukin-6 ( IL-6) ，and vascular endothelial growth factor ( VEGF) levels were measured at the beginning of enrollment and 2 months after treatment，and the quality of life of patients was evaluated by Diabetes Spe- cific Quality of Life Scale ( DSQL) ． Ｒesults: The total effective rate of treatment in the observation group was higher than that in the control group ( 92． 31% vs． 82． 18% ，P ＜ 0． 05) ． After treatment，CMT，BCVA，ＲI，serum IL-6，and VEGF levels in the observation group were lower than those in the control group，and the levels of PSV and EDV were higher than those in the control group ( P ＜ 0. 05) ． The total incidence of complications in the observation group was lower than that in the control group ( 6． 73% vs． 21. 78% ，P ＜ 0． 05) ． The DSQL scores of diabetic patients in the observation group were significantly lower than those in the control group ( P ＜ 0． 05) ． Conclusion: Ｒetinal laser photocoagulation combined with Volitin can improve vision and local retinal microcircula- tion disorders in patients with diabetic retinopathy，reduce inflammation，and reduce complications． 【Key words】Diabetic retinopathy; Ｒetinal laser photocoagulation; Volitin; Vision; Local retinal microcirculation
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视网膜激光光凝术联合沃丽汀对糖尿病视网膜病变的临床疗效_向一旻.pdf |
